ESPE Abstracts

Background: Turner syndrome (TS) is one of the most common causes of short stature in females. Adult height of patients with TS is 20 cm shorter than in general population. GH therapy improves height outcome in girls with TS; results depend on age at diagnosis, duration of therapy, and doses of GH.Objective: To evaluate growth and safety during the first 4 years of GH treatment in patients with TS.Method: Eight prepubertal girls wi...

Background: GH therapy is being used worldwide to improve height outcome in children with GH deficiency (GHD), with minimal serious side effects. Early diagnosis and therapy initiation optimize growth outcomes.Objectives: To evaluate growth and safety during the first 4 years of GH treatment in 33 GHD children.Methods: We reviewed clinical data of 33 prepubertal children (23 boys and ten girls): 30 with isolated GH deficiency (IGHD...

Background: Children born small for gestational age (SGA) are predisposed to metabolic abnormalities. While the therapeutic benefit of recombinant human growth hormone (rhGH) therapy in improving height is widely recognised, it can affect carbohydrate metabolism, potentially inducing diabetes.Objective and hypotheses: This ongoing, prospective study aims to evaluate the long-term safety and efficacy of Omnitrope® (somatropin) in children ...